25 Mart 2020 Çarşamba

Hanta virüsü Virions

Hanta virüsü- Virions

Virion
Nükleik asit ve protein kılıfından oluşan tam bir virüs partikülü. Virion. Enfekte etme yeteneğine sahip veya etkin olan tam virüs




Hantavirus virions are about 120–160 nanometers (nm) in diameter. The lipid bilayer of the viral envelope is about 5 nm thick and is embedded with viral surface proteins to which sugar residues are attached. These glycoproteins, known as Gn and Gc, are encoded by the M segment of the viral genome. They tend to associate (heterodimerize) with each other and have both an interior tail and an exterior domain that extends to about 6 nm beyond the envelope surface.
Inside the envelope are the nucleocapsids. These are composed of many copies of the nucleocapsid protein N, which interact with the three segments of the viral genome to form helical structures. The virally encoded RNA polymerase is also found in the interior. By mass, the virion is greater than 50% protein, 20–30% lipid and 2–7% carbohydrate. The density of the virions is 1.18 gram per cubic centimeter. These features are common to all members of the Hantaviridae family.


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